[Approaches to the pre-operative functional assessment of patients with lung cancer and preoperative rehabilitation].

Pôle de pathologie thoracique, service de physiologie et d'explorations fonctionnelles, hôpitaux universitaires de Strasbourg, Strasbourg, France. Electronic address: anne.charloux@chru-strasbourg.fr. Pôle de pathologie thoracique, service de physiologie et d'explorations fonctionnelles, hôpitaux universitaires de Strasbourg, Strasbourg, France. Pôle de pathologie thoracique, service de chirurgie thoracique, hôpitaux universitaires de Strasbourg, Strasbourg, France; Inserm UMR 1260, nanomédecine régénérative, fédération de médecine translationnelle, université de Strasbourg, Strasbourg, France.

Revue des maladies respiratoires. 2020;(10):800-810

Abstract

Surgery is the best treatment for early lung cancer but requires a preoperative functional evaluation to identify patients who may be at a high risk of complications or death. Guideline algorithms include a cardiological evaluation, a cardiopulmonary assessment to calculate the predicted residual lung function, and identify patients needing exercise testing to complete the evaluation. According to most expert opinion, exercise tests have a very high predictive value of complications. However, since the publication of these guidelines, minimally-invasive surgery, sublobar resections, prehabilitation and enhanced recovery after surgery (ERAS) programmes have been developed. Implementation of these techniques and programs is associated with a decrease in postoperative mortality and complications. In addition, the current guidelines and the cut-off values they identified are based on early series of patients, and are designed to select patients before major lung resection (lobectomy-pneumonectomy) performed by thoracotomy. Therefore, after a review of the current guidelines and a brief update on prehabilitation (smoking cessation, exercise training and nutritional aspects), we will discuss the need to redefine functional criteria to select patients who will benefit from lung surgery.

Methodological quality

Publication Type : Review

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